Unleashing the Possibilities and Promise of Topical Delivery

Our solution

Stratum Biosciences uses AI + biomarker discovery to create new therapies and revolutionize molecular delivery across the skin.

SkinSyncTM ingredients pass the barrier and reach skin targets in a predictable way
Who we are

About
Stratum Biosciences

Touch your elbow. Then your nose. Feel the difference? Those differences are everything for treating skin disease — or delivering systemic therapies through skin. Nobody has had the tools to discover and integrate these insights. Until now.

21st Century Skin Challenges,
Meet 21st Century Solutions.

What do conditions like hair loss, skin cancer, and warts have in common?

They are all difficult to treat because disease targets are locked beneath tough skin barriers.

  • 4690000000

    Number of new cases of skin, hair, and nail diseases per year

    As reported by Global Burden of Disease Report 2021.
  • 41900000

    Years of healthy, disability-free life lost per year from skin diseases

We're discovering new biomarkers of skin health to find treatments and cures faster than ever.

Meet the team

Dermatology-Driven Biotech

Ross L. Pearlman, MD
Chief Executive Officer, Co-Founder
  • Dual-fellowship trained cosmetic dermatologist and dermatologic surgeon from Northwestern University
  • Named “Rising Star” of dermatology (2021)
  • Three national awards for innovation in dermatology, author of 40+ publications and 5 textbook chapters on skin
Buu T. Duong, MD
President, Co-Founder
  • Board-certified dermatopathologist
  • Tripled business revenue in three years as Managing Partner of Dermatopathology Associates, PLLC
  • Expert in digital pathology, revenue cycle management, and laboratory information systems
David Osborne, PhD
Key Advisor, Co-Inventor
  • World-renowned expert on topical formulations and skin barrier
  • Co-Founder, former CTO of Arcutis Biotherapeutics (ARQT)
  • Over 40 patents and inventions
  • Invented, launched several of the most commercially successful topical drugs (Zoryve™)
Peter Lio, MD
Pre-Seed Lead, Key Advisor
  • Harvard-trained leader in dermatology
  • Top 5 world expert on inflammatory skin diseases, >200 publications on skin
  • Invested, advised, and consulted for dozens of personal care and pharmaceutical companies
  • Key role in design, patent, and commercialization of Theraplex™ AIM
Our platform

Passing the skin barrier

With Precise Navigation, Our Platform:

  • Reduces physical barrier disruption
  • Increases efficacy
  • Minimizes side effects and inflammation
  • Unlocks new targets
  • Decreases costs
SkinSync™ Designed: Ingredients pass the barrier and reach skin targets in a predictable way
SkinSync™ Designed: Ingredients pass the barrier and reach skin targets in a predictable way

We deliver actives without breaking skin

1

Pinpoint Underperforming Actives

With poor clinical efficacy

2

Transform Using AI/ML


Maximize permeability, activity, and tolerability by editing Active-Vehicle System

3

Create New Products and IP


Novel and Effective Bioactive Ingredient

Powering our proprietary AI/ML insights

  • 200000 +

    Real skin samples for training

  • 50 +

    Clinical & Physicochemical variables

  • 7000 +

    Standardized experiments

Partner With Us!

Revolutionize Skin Health Together

If you’re seeking to refine your actives, improve your formulation chassis, or co-create next-generation skincare or pharmaceutical solutions, we’d love to collaborate.

Partner with us to unlock new possibilities in dermatology and change the paradigm for skin disease.

Let’s innovate.

Contact Us to explore partnership opportunities.



Our Advantages

Next-Gen Skin Delivery

Our proprietary topical delivery platform is purpose-built for skin indications and backed by strong intellectual property. Designed with precision, it ensures targeted, effective results across dermatological applications.

Targeted Skin Delivery

Smarter Innovation Engine

Driven by an AI system built on trade-secret insights, our flexible platform adapts to multiple conditions. Every advancement is rapidly validated through our Lab-in-the-Loop framework, ensuring speed, accuracy, and scientific rigor.

AI-Driven Discovery