Leveraging AI and skin science to eliminate bad skin days

Our solution

Stratum Biosciences transforms ineffective, impermeable molecules into high-performance, novel bioactives that preserve barrier integrity and eliminate inflammation.

SkinSyncTM ingredients pass the barrier and reach skin targets in a predictable way
Who we are

About
Stratum Biosciences

We developed the first AI-powered design platform built specifically for topical products to create the most effective, gentle, and sustainable compounds for helping people of all skin types achieve their best skin, everyday.

21st Century Skin Challenges,
Meet 21st Century Solutions.

Despite modern advancements, achieving healthy skin is more challenging than ever.

Environmental factors—like rising pollution, antimicrobial resistance, ozone depletion, and intense UV exposure—impact our skin daily, exacerbating irritation, redness, and premature aging.

  • 3600

    Average number of bad skin days in an American lifetime

    As reported by SWNS Digital 2021.
  • 45 %

    Of the population with chronic redness or inflammation of skin

    Geth et al. Brit J Derm. 2018.

Our AI-powered dermatology platform addresses these challenges, providing optimized solutions for healthy, resilient skin of all types.

Meet the team

Dermatology-Driven Biotech

Ross L. Pearlman, MD
Chief Executive Officer, Co-Founder
  • Dual-fellowship trained cosmetic dermatologist and dermatologic surgeon from Northwestern University
  • Named “Rising Star” of dermatology (2021)
  • Three national awards for innovation in dermatology, author of 40+ publications and 5 textbook chapters on skin
Buu T. Duong, MD
President, Co-Founder
  • Board-certified dermatopathologist
  • Tripled business revenue in three years as Managing Partner of Dermatopathology Associates, PLLC
  • Expert in digital pathology, revenue cycle management, and laboratory information systems
David Osborne, PhD
Key Advisor, Co-Inventor
  • World-renowned expert on topical formulations and skin barrier
  • Co-Founder, former CTO of Arcutis Biotherapeutics (ARQT)
  • Over 40 patents and inventions
  • Invented, launched several of the most commercially successful topical drugs (Zoryve™)
Peter Lio, MD
Pre-Seed Lead, Key Advisor
  • Harvard-trained leader in dermatology
  • Top 5 world expert on inflammatory skin diseases, >200 publications on skin
  • Invested, advised, and consulted for dozens of personal care and pharmaceutical companies
  • Key role in design, patent, and commercialization of Theraplex™ AIM
Our platform

Passing the skin barrier

With Precise Navigation, Our Platform:

  • Reduces physical barrier disruption
  • Increases efficacy
  • Minimizes side effects and inflammation
  • Unlocks new targets
  • Decreases costs
SkinSync™ Designed: Ingredients pass the barrier and reach skin targets in a predictable way
SkinSync™ Designed: Ingredients pass the barrier and reach skin targets in a predictable way

We deliver actives without breaking skin

1

Pinpoint Underperforming Actives

With poor clinical efficacy

2

Transform Using AI/ML


Maximize permeability, activity, and tolerability by editing Active-Vehicle System

3

Create New Products and IP


Novel and Effective Bioactive Ingredient

Powering our proprietary AI/ML insights

  • 50000 +

    Real skin samples for training

  • 50 +

    Clinical & Physicochemical variables

  • 3000 +

    Standardized experiments

Topical Pipeline

Primary use
Design
In Vitro Testing
Safety Testing & Formulation
Clinical Testing
Hyperpigmentation (Skin Brightener, Melasma, Post-inflammatory)
Redness (Rosacea)
Fine lines and Wrinkles
Partner With Us!

Revolutionize Skin Health Together

If you’re seeking to refine your actives, improve your formulation chassis, or co-create next-generation skincare solutions, we’d love to collaborate.

Partner with us to unlock new possibilities in dermatology and deliver exceptional outcomes for all skin types.

Let’s innovate.

Contact Us to explore partnership opportunities.



Our Advantages

AI/ML platform powered by proprietary insights

  • Data based on real-life skin modeling
  • Core team with combined 75+ years expertise in skincare, formulation, biotech, and pharmaceuticals

End-to-end design of active-vehicle systems

  • Preserves the natural skin barrier
  • Minimizes inflammation and irritation
  • Promotes patient and consumer tolerability and compliance