Unleashing the Power of Biology + AI to Build Healthier Skin

Our solution

At Stratum, we’re building the foundations for the next era of human skin health.

Using SkinSync™, the first AI platform dedicated to skin science, we translate deep biological insights into new skincare technology to powers tomorrow’s products.

We create novel active ingredients and formulations aimed at dermatology’s toughest problems from cellular aging to oxidative stress to hyperpigmentation.

SkinSyncTM ingredients pass the barrier and reach skin targets in a predictable way
Who we are

About
Stratum Biosciences

Skin is the largest organ in the human body—and one of the least understood.

We all know skin is different across the body. The skin on our nose feels nothing like the skin on our elbow. But until recently, we haven’t been able to explain why on a quantitative level.

Because of this complexity, most skincare technology is built through trial and error discovery that takes years, costs millions, and often fails late — whether you’re a startup or a global consumer brand.

21st Century Skin Challenges,
Meet 21st Century Solutions.

For the first time, Stratum has built the tools to study skin science at scale and use those insights to invent product solutions.

By understanding how skin varies across body regions and conditions — and what changes when skin breaks down through aging, inflammation, or disease— SkinSync™ speeds design of novel active ingredients and optimizes delivery of those ingredients through the skin barrier.

  • 4690000000

    Number of new cases of skin, hair, and nail diseases per year

    As reported by Global Burden of Disease Report 2021.
  • 41900000

    Years of healthy, disability-free life lost per year from skin diseases

Using SkinSync™, we deliver new product technologies over 5x faster.

We deliver actives without breaking skin

1

Pinpoint Underperforming Actives

With poor clinical efficacy

2

Transform Using AI/ML


Maximize permeability, activity, and tolerability by editing Active-Vehicle System

3

Create New Products and IP


Novel and Effective Bioactive Ingredient

Powering our proprietary AI/ML insights

  • 200000 +

    Real skin samples for training

  • 50 +

    Clinical & Physicochemical variables

  • 7000 +

    Standardized experiments

Meet the team

Dermatology-Driven Biotech

Ross L. Pearlman, MD
Chief Executive Officer, Co-Founder
  • Dual-fellowship trained cosmetic dermatologist and dermatologic surgeon from Northwestern University
  • Named “Rising Star” of dermatology (2021)
  • Three national awards for innovation in dermatology, author of 40+ publications and 5 textbook chapters on skin
Buu T. Duong, MD
President, Co-Founder
  • Board-certified dermatopathologist
  • Tripled business revenue in three years as Managing Partner of Dermatopathology Associates, PLLC
  • Expert in digital pathology, revenue cycle management, and laboratory information systems
David Osborne, PhD
Key Advisor, Co-Inventor
  • World-renowned expert on topical formulations and skin barrier
  • Co-Founder, former CTO of Arcutis Biotherapeutics (ARQT)
  • Over 40 patents and inventions
  • Invented, launched several of the most commercially successful topical drugs (Zoryve™)
Peter Lio, MD
Pre-Seed Lead, Key Advisor
  • Harvard-trained leader in dermatology
  • Top 5 world expert on inflammatory skin diseases, >200 publications on skin
  • Invested, advised, and consulted for dozens of personal care and pharmaceutical companies
  • Key role in design, patent, and commercialization of Theraplex™ AIM
Partner With Us!

Revolutionize Skin Health Together

If you’re seeking to refine your actives, improve your formulation chassis, or co-create next-generation skincare or pharmaceutical solutions, we’d love to collaborate.

Partner with us to unlock new possibilities in dermatology and change the paradigm for skin disease.

Let’s innovate.

Contact Us to explore partnership opportunities.



Our Advantages

Next-Gen Skin Delivery

Our proprietary topical delivery platform is purpose-built for skin indications and backed by strong intellectual property. Designed with precision, it ensures targeted, effective results across dermatological applications.

Targeted Skin Delivery

Smarter Innovation Engine

Driven by an AI system built on trade-secret insights, our flexible platform adapts to multiple conditions. Every advancement is rapidly validated through our Lab-in-the-Loop framework, ensuring speed, accuracy, and scientific rigor.

AI-Driven Discovery